Anticoagulants


Description of the pharmacological group

Anticoagulative (anti-thrombotic) means

The means, which reduce coagulation of the blood, it adapts in cardiology for the preventive maintenance of thrombogenesis in patients, who transferred myocardial infarction.

Anticoagulants of direct and indirect action, the preparations of low-molecular heparin

Anticoagulants - medicines, which impede formation of filament of fibrin and thrombogenesis, contribute to the curtailment of an increase in the already emergent dust devils, and also to action on the dust devils of endogenous fibrinolytic ferments.

Anticoagulants

Anticoagulants are subdivided into two groups:

1) the anticoagulants of direct action - heparin, nadroparin calcium, enoxaparin sodium and so forth;

2) the anticoagulants of indirect action - acenocoumarol, warfarin, phenindione, ethyl biscoumacetate and other

Anticoagulants of the direct action

 Heparin is the endogenous biologically active substance, for the first time isolated from the liver of mammals in 1916. The substance obtained from the liver was called name “heparin”, i.e., isolated or locating in the liver.

Anticoagulants of the indirect action

The anticoagulants of indirect action include preparty of acenocoumarol (sin.: syncumar), coumadin, phenindione (sin.: phenyline), ethyl biscoumacetate (sin.: neodicumarin) and other


Anticoagulants are used for treatment of heart failure, hypertension, acute myocardial infarction

Summary

Prevention of thrombosis in patients after myocardial infarction