Hemostatic means (procoagulants)
This information is not intended for purposes of treatment without physician.
Description of the pharmacological group
The medicines, which increase the coagulability of the blood
The medicines, which increase the coagulability of the blood, or the hemostatic means include the coagulants of direct and indirect action, the inhibitors of fibrinolysis, the antagonists of heparin, means for treating hemophilia, hemostatic of medicines of plant origin, Thrombogenic medicines.
In the clinical practice these medicines use for preventive maintenance and treating the hemorrhages. The disturbances of hemostasis can develop as a result the suppression of adhesion and/or aggregation of thrombocytes, sharp making more active of the processes of fibrinolysis, genetically caused by scarcity factors of coagulation of the blood, and also as a result traumatic operations, especially on the cloths of lungs and liver, some intoxications, radiation sickness.
Hemostatic means (procoagulants) are medicines, which facilitate formation and retention of dust devil. The system of hemostasis includes three closely interconnected the process: 1) cellular primary hemostasis; 2) plasma (second) hemostasis; 3) fibrinolysis. In each of these processes are present the factors, whose action is directed toward the retention of the constancy of the internal medium of organism (maintenance of the blood in the liquid state, if necessary the formation of dust devil).
Classification
Hemostatic action the preparations, which influence different stages of hemostasis, possess:
1) Antagonists of heparin (protamine sulfate).
2) Serotonin adipate as the activator of cellular hemostasis (see “serotonin and serotoninergic and anti-serotonin preparations”).
3) Activators of plasma hemostasis (menadione, phytomenadione and other).
4) Inhibitors of fibrinolysis (aminocaproic acid, pamba, transamcha, contrycal, gordox and other).
The straight coagulants of this group include salts of calcium (chloride, gluconate), used locally the sponge and fibrin film isogenous and other
Hemostatic are used for treatment of heart failure, hypertension, acute myocardial infarction