Cholestyramine (Cholestyraminum)
CHOLESTYRAMINE
Synonyms:
Cholestyramine, Cholestyraminum, Colestyramin, Divistyramine, Nolestan, Ipocol, Questran
Description
Acting substance - Cholestyramine: polymer chloride of styrene with the divinylbenzene and the aliphatically connected quaternary ammonium groups. It is the anion exchange resin, which forms with the entering into the bowels the nonabsorbed complexes c by bilious acids, which leads to strengthening of the removal of bilious acids from the organism and decreasing the suction of cholesterol in the bowels.
Pharmacological action
With the method per os it is not sucked and in the unchanged form is derived with the feces. In the bowels are formed the nonabsorbed complexes, which contributes to strengthening their removal from the organism and decreasing the suction of cholesterol in the bowels.
Indications for use
Itch, caused by the stagnation of the bile as a result of the diseases of the liver (gallstone disease, the traumatic postoperative strictures of bile tracts, carcinoma and other); hypercholesterolemia, poisoning by the preparations of digitalis.
Method of application and dose
Inward on 1 tea spoon (4 d) of 2 times in the day. Daily dose can be increased to 16 g (into 4 methods). If it is necessary to appoint other per os preparations, then after the method of cholestyramine is required interval not less than 4 hours.
Side-line action
Are possible nausea, vomiting, diarrhea or bolts. Treatment is conducted under the control of prothrombin index.
Contraindications
Hypersensitivity; the impassability of the bile-secreting ways, phenylketonuria, pregnancy (and suspicion to it), the period of lactation.Precautions. Age is older than 60 years.
Form of the release
Powder in the bottles until 500.
Storage
In the dry cool place.